Denosumab (International Nonproprietary Name)

Solution for injection
Available forms may vary by country. Please refer to your local label.

Subcutaneous use (injection under the skin)

This medicine is used to treat bone loss and reduce the risk of fractures in specific adult populations, as advised by a healthcare professional. These include:
• Postmenopausal women and men with osteoporosis who are at increased risk of fractures
• Men with prostate cancer undergoing hormone therapy
• Adults receiving long-term systemic glucocorticoid treatment who are at increased risk of fractures
Approved uses may differ by country. Always refer to the locally approved product information.

Denosumab is a prescription medicine available as a pre-filled syringe for injection. It is typically administered once every six months by a trained healthcare professional.
Patients receiving this treatment are usually advised to take calcium and vitamin D supplements to support bone health.

Denosumab works by targeting a protein in the body called RANKL. This protein plays a role in the development and activity of cells that break down bone. By blocking RANKL, denosumab helps reduce bone loss and maintain bone strength.

Bone-modifying agent (RANKL inhibitor)

This page is intended for general informational purposes only and does not replace professional medical advice. Product availability, indications, and labelling may vary by country. Like all drugs, this medicine may cause side effects. Talk to your doctor if you experience any unusual symptoms. Always consult your healthcare provider and refer to the locally approved product information.